{
  "dataset": "studies",
  "name": "Research timeline",
  "description": "Peer-reviewed and agency research on engineered-stone silicosis, checked against PubMed.",
  "page": "https://silicosislawsuit.com/research/",
  "license": "CC BY 4.0, attribution to silicosislawsuit.com",
  "record_count": 11,
  "last_verified": "2026-09-12",
  "records": [
    {
      "study_id": "fazio-2023-jamaim",
      "title": "Silicosis Among Immigrant Engineered Stone (Quartz) Countertop Fabrication Workers in California",
      "authors": "Fazio JC, Gandhi SA, Flattery J, et al.",
      "journal": "JAMA Internal Medicine",
      "year": 2023,
      "date": "2023-09-01",
      "doi": "10.1001/jamainternmed.2023.3295",
      "pmid": "37486642",
      "type": "Case series (CDPH surveillance 2019-2022)",
      "jurisdiction": "California",
      "key_findings": [
        "52 male patients, median age 45; 51 Latino immigrants; 19% uninsured",
        "Diagnosis delayed in 58%; 38% had progressive massive fibrosis at diagnosis; 19% fatal, median age at death 46"
      ],
      "significance": "The paper most cited in coverage of the California outbreak.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "fazio-2025-jomt-review",
      "title": "A review of silicosis and other silica-related diseases in the engineered stone countertop processing industry",
      "authors": "Fazio JC, Viragh K, Houlroyd J, et al.",
      "journal": "Journal of Occupational Medicine and Toxicology",
      "year": 2025,
      "date": "2025-03-17",
      "doi": "10.1186/s12995-025-00455-8",
      "pmid": "40098042",
      "type": "Narrative review",
      "jurisdiction": "International",
      "key_findings": [
        "Engineered stone is over 90% crystalline silica versus 40-50% for granite and under 10% for marble",
        "Disease diagnosed after 7-19 years of exposure; exposures often exceed limits even with wet saws and ventilation"
      ],
      "significance": "Current clinical and regulatory overview.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "flattery-2025-ajph",
      "title": "Silicosis Surveillance in California, 2019-2024: Tracking an Epidemic",
      "authors": "Flattery J, Woolsey C, Fazio JC, et al.",
      "journal": "American Journal of Public Health",
      "year": 2025,
      "date": "2025-11",
      "doi": "10.2105/AJPH.2025.308225",
      "pmid": "40906995",
      "type": "Surveillance analysis",
      "jurisdiction": "California",
      "key_findings": [
        "296 confirmed silicosis cases 2019-2024, 243 (82%) associated with engineered stone",
        "Engineered-stone cases younger, male, Latino and concentrated in Los Angeles County; 25% referred for transplant"
      ],
      "significance": "Describes how CDPH's multisource surveillance works and its limits.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "gandhi-2026-ats-workshop",
      "title": "Silicosis in the Artificial Stone Countertop Industry: An Official American Thoracic Society Workshop Report",
      "authors": "Gandhi SA, Liu GY, Fazio JC, et al.",
      "journal": "Annals of the American Thoracic Society",
      "year": 2026,
      "date": "2026-06-26",
      "doi": "10.1093/annalsats/aaoag176",
      "pmid": "42363709",
      "type": "Professional society workshop report",
      "jurisdiction": "International",
      "key_findings": [
        "Artificial-stone dust contains high silica plus resin-derived volatiles and trace metals; exposures routinely exceed limits despite wet methods, ventilation and respirators",
        "High rates of progressive massive fibrosis, autoimmune disease, infection and transplant need"
      ],
      "significance": "Consensus statement of the leading US respiratory society.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "heinzerling-2026-nejm-evid",
      "title": "Silicosis among Workers Fabricating Engineered Stone ('Quartz') Countertops in California, 2019-2026",
      "authors": "Heinzerling A, Flattery J, Cummings KJ, et al.",
      "journal": "NEJM Evidence",
      "year": 2026,
      "date": "2026-09",
      "doi": "10.1056/EVIDpha2600187",
      "pmid": "42584953",
      "type": "Public health surveillance report",
      "jurisdiction": "California",
      "key_findings": [
        "592 cases identified January 2019 through June 2026; 65 lung transplants; 31 deaths",
        "Median age at diagnosis 46; 98% Latino; nearly all male; median 22 years of occupational silica exposure (per Healio's report of the paper)"
      ],
      "significance": "Most complete published account of the California outbreak.",
      "sources": [
        "pubmed",
        "cidrap-2026-09",
        "healio-2026-09-11"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "hoy-2018-oem",
      "title": "Artificial stone-associated silicosis: a rapidly emerging occupational lung disease",
      "authors": "Hoy RF, Baird T, Hammerschlag G, et al.",
      "journal": "Occupational and Environmental Medicine",
      "year": 2018,
      "date": "2018-01",
      "doi": "10.1136/oemed-2017-104428",
      "pmid": "28882991",
      "type": "Case series",
      "jurisdiction": "Australia",
      "key_findings": [
        "Seven male workers, median age 44, all dry-cutting artificial stone in small shops",
        "Median 7 years' exposure before symptoms; six had progressive massive fibrosis with rapid lung-function decline"
      ],
      "significance": "Australian series that preceded the national screening programme and ban.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "hoy-2025-ajim-victoria",
      "title": "The Rapid Rise of Silicosis in Victoria, Australia Associated With Artificial Stone Countertop Industry Work",
      "authors": "Hoy RF, Tomic D, Gwini S, et al.",
      "journal": "American Journal of Industrial Medicine",
      "year": 2025,
      "date": "2025-04",
      "doi": "10.1002/ajim.23704",
      "pmid": "39829386",
      "type": "Compensation-claims and registry analysis",
      "jurisdiction": "Victoria, Australia",
      "key_findings": [
        "536 silicosis compensation claims over 32 years, 90% of them in 2015-2022 (a 27-fold rise)",
        "Of 210 registry cases 2019-2022, 97% worked in the countertop industry and 89% were found through government screening"
      ],
      "significance": "Shows how active screening surfaces cases that would otherwise go unrecognised.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "kramer-2012-chest",
      "title": "Artificial stone silicosis: disease resurgence among artificial stone workers",
      "authors": "Kramer MR, Blanc PD, Fireman E, et al.",
      "journal": "Chest",
      "year": 2012,
      "date": "2012-08",
      "doi": "10.1378/chest.11-1321",
      "pmid": "22383661",
      "type": "Retrospective cohort",
      "jurisdiction": "Israel",
      "key_findings": [
        "25 silicosis patients referred for lung transplant evaluation 1997-2010, all exposed by dry-cutting a high-silica artificial stone",
        "10 underwent transplantation; observed transplant incidence 14.6 times the ISHLT-registry expectation"
      ],
      "significance": "First major clinical series linking engineered stone to a silicosis outbreak.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "leso-2019-ijerph",
      "title": "Artificial Stone Associated Silicosis: A Systematic Review",
      "authors": "Leso V, Fontana L, Romano R, et al.",
      "journal": "International Journal of Environmental Research and Public Health",
      "year": 2019,
      "date": "2019-02-16",
      "doi": "10.3390/ijerph16040568",
      "pmid": "30781462",
      "type": "Systematic review",
      "jurisdiction": "International",
      "key_findings": [
        "Disease characteristics comparable to traditional silicosis but with gaps in exposure assessment and control in the artificial-stone sector"
      ],
      "significance": "Early synthesis of the international literature.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "rose-2019-mmwr",
      "title": "Severe Silicosis in Engineered Stone Fabrication Workers: California, Colorado, Texas, and Washington, 2017-2019",
      "authors": "Rose C, Heinzerling A, Patel K, et al.",
      "journal": "MMWR Morbidity and Mortality Weekly Report",
      "year": 2019,
      "date": "2019-09-27",
      "doi": "10.15585/mmwr.mm6838a1",
      "pmid": "31557149",
      "type": "Case report series",
      "jurisdiction": "United States (CA, CO, TX, WA)",
      "key_findings": [
        "18 cases including the first two US fatalities in the stone fabrication industry",
        "Several with progressive disease, autoimmune disease and latent tuberculosis"
      ],
      "significance": "First CDC report of the US outbreak.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    },
    {
      "study_id": "surasi-2022-ajim",
      "title": "Elevated exposures to respirable crystalline silica among engineered stone fabrication workers in California, January 2019-February 2020",
      "authors": "Surasi K, Ballen B, Weinberg JL, et al.",
      "journal": "American Journal of Industrial Medicine",
      "year": 2022,
      "date": "2022-09",
      "doi": "10.1002/ajim.23416",
      "pmid": "35899403",
      "type": "Exposure assessment from Cal/OSHA inspections",
      "jurisdiction": "California",
      "key_findings": [
        "152 employees at 47 workplaces sampled; 25% of employees above the PEL (median 89.7 ug/m3, up to 670.7)",
        "72% of workplaces cited for at least one RCS standard violation"
      ],
      "significance": "Documents widespread overexposure in California shops before the 2023 emergency standard.",
      "sources": [
        "pubmed"
      ],
      "verification_status": "verified_primary",
      "last_verified": "2026-09-12"
    }
  ]
}